Xilis
Revolutionizing Drug Discovery and Development with Patient-Derived MicroOrganoSpheres®
Durham, United States · Founded 2019 · $92.0M raised
- Headquarters
- Durham, North Carolina
- Employees
- 51–200
- Founded
- 2019
- Business Model
- B2B
- Website
- xilis.com
- Total Funding
- $92.0M
- Last Round
- $19.0M Series AApr 2025
- Rounds
- 3
About
Xilis develops advanced patient-derived organoid technology to accelerate pharmaceutical development and improve cancer treatment outcomes. The company's proprietary MicroOrganoSphere® (MOS) platform creates 3D micro-tumor models that preserve the cellular composition, genetic alterations, immune microenvironment, and histopathology of primary patient tissue. These models enable more accurate drug efficacy predictions and reduce risk throughout the drug discovery and development lifecycle—from initial discovery through clinical trials—spanning immuno-oncology, chemotherapy, and cell therapy applications. The platform integrates automated model creation, customizable assays, and AI-powered analytics to support both precision oncology diagnostics and pharmaceutical R&D partnerships.
Summary
Xilis is a Biotech company based in Durham, United States, founded in 2019. It has raised $92.0M in total across 3 rounds, most recently a $19.0M Series A round in Apr 2025. Investors include Felicis Ventures, Fpv Ventures and Mubadala Capital.
Tech & App Stack
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Funding History
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Apr 2025
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Seed through Series A — per-round amounts, valuations, and who invested in each round.
Investors

Felicis Ventures
2 rounds
Fpv Ventures
1 round
Mubadala Capital
1 round

Pear VC
2 rounds

Alexandria Venture Investments
1 round
EQT AB
1 round
GV (Google Ventures)
1 round
Two Sigma Ventures
1 round
KdT Ventures
1 round

Alix Ventures
1 round
LSP Life Sciences Partners
1 round
Liquid 2 Ventures
1 round

8VC
1 round
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