Xilis

Revolutionizing Drug Discovery and Development with Patient-Derived MicroOrganoSpheres®

Durham, United States · Founded 2019 · $92.0M raised

Employees
51–200
Founded
2019
Business Model
B2B
Website
xilis.com
Total Funding
$92.0M
Last Round
$19.0M Series AApr 2025
Rounds
3

About

Xilis develops advanced patient-derived organoid technology to accelerate pharmaceutical development and improve cancer treatment outcomes. The company's proprietary MicroOrganoSphere® (MOS) platform creates 3D micro-tumor models that preserve the cellular composition, genetic alterations, immune microenvironment, and histopathology of primary patient tissue. These models enable more accurate drug efficacy predictions and reduce risk throughout the drug discovery and development lifecycle—from initial discovery through clinical trials—spanning immuno-oncology, chemotherapy, and cell therapy applications. The platform integrates automated model creation, customizable assays, and AI-powered analytics to support both precision oncology diagnostics and pharmaceutical R&D partnerships.

Summary

Xilis is a Biotech company based in Durham, United States, founded in 2019. It has raised $92.0M in total across 3 rounds, most recently a $19.0M Series A round in Apr 2025. Investors include Felicis Ventures, Fpv Ventures and Mubadala Capital.

Tech & App Stack

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Funding History

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Series ASeries AApr 2025
$19.0M

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Seed through Series A — per-round amounts, valuations, and who invested in each round.

Investors

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