Upstream Bio
IPOHomepage
Public · Waltham, United States · Founded 2021 · $400.0M raised
- Headquarters
- Waltham, Massachusetts
- Employees
- 51–200
- Founded
- 2021
- Business Model
- B2B
- Website
- upstreambio.com
- Total Funding
- $400.0M
- Last Round
- $200.0M Series BJun 2023
- Rounds
- 2
- Type
- Public
Totals include recorded grants and other qualifying funding, not just equity. What counts toward funding.
About
Upstream Bio is a clinical-stage biotechnology company developing verekitug, the only known TSLP receptor antagonist in clinical development for inflammatory diseases. The company has advanced verekitug into three Phase 2 clinical trials across chronic rhinosinusitis with nasal polyps, severe asthma, and COPD, with an experienced team focused on severe respiratory diseases.
Summary
Upstream Bio is a Biotech company based in Waltham, United States, founded in 2021. It has raised $400.0M in total across 2 rounds, most recently a $200.0M Series B round in Jun 2023. Investors include OrbiMed, Maruho Co., Ltd. and Enavate Sciences.
Tech & App Stack
4 technologies & apps tracked
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Funding & Exit History
Oct 2024
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Funding: Series A through Series B. Amounts, valuations, and investors where available.
Investors
OrbiMed
2 rounds
Maruho Co., Ltd.
2 rounds
Enavate Sciences
1 round

Venrock
1 round
Bain Capital Life Sciences
1 round
Wellington Management
1 round
Decheng Capital
1 round
HBM Healthcare Investments
1 round
TCGX
1 round
Omega Funds
1 round

Samsara BioCapital
1 round
Altshuler Shaham Provident Funds Ltd.
1 round
Access Industries
1 round
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