
Pioneering microRNA therapeutics for serious diseases
Regulus Therapeutics is a biopharmaceutical company founded in 2007 as a joint venture between Alnylam Pharmaceuticals and Ionis Pharmaceuticals. The company pioneered the development of oligonucleotide therapeutics that inhibit dysregulated microRNA targets. Its lead program, farabursen (RGLS8429), targeted ADPKD, the most common genetic cause of renal failure. In April 2025, Novartis agreed to acquire Regulus for up to $14 per share, valuing the deal at approximately $1.7 billion.
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