Perlara

Perlara: building the YC for rare disease parents

Oakland, United States · Founded 2014 · $1.0M raised

Employees
1–10
Founded
2014
Total Funding
$1.0M
Last Round
$1.0M GrantSep 2025
Rounds
3

About

Perlara 1.0 (Feb 2014 - Feb 2019) launched early R&D joint ventures called PerlQuests with highly motivated rare disease families, companies or impact investors. We screened gene-edited patient avatars for repurposable drugs in order to build a predictive R&D engine called ArkBase. We planned to monetize programs based on ArkBase predictions by selectively spinning out asset-centric clinical development NewCos. Perlara 1.5 (March 2019 - April 2020) was the transition to a one-person virtual clinical development company and when the epalrestat and aripiprazole repurposing trials were launched at Mayo Clinic for the treatment of PMM2-CDG and NGLY1-CDDG, respectively. Perlara 2.0 (May 2020 --> The first decentralized and distributed biotech

Summary

Perlara is a Healthcare company based in Oakland, United States, founded in 2014. It has raised $1.0M in total across 3 rounds, most recently a $1.0M Grant round in Sep 2025. Investors include Y Combinator, Slow Ventures and Novartis Venture Fund.

Tech & App Stack

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Funding History

GrantSBIR Phase II (NIH)Sep 2025
$1.0M

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