Iterion Therapeutics

Total Funding
$24.1M
Last Round
$7.1M GrantNov 2025
Rounds
2

About

Iterion Therapeutics is developing tegavivint, a novel small-molecule inhibitor that binds to TBL1 and disrupts the interaction between beta-catenin and TBL1, promoting degradation of nuclear beta-catenin and preventing transcription of Wnt/beta-catenin targeted oncogenes. Preclinical studies have shown tegavivint inhibits beta-catenin activity without overt toxicity and is not affected by CTNNB1 gain-of-function mutations typically found in cancer cells. In parallel with the tegavivint program, Iterion has ongoing R&D programs investigating and developing second-generation TBL1 inhibitors.

Summary

Iterion Therapeutics is a Biotech company. It has raised $24.1M in total across 2 rounds, most recently a $7.1M Grant round in Nov 2025. Investors include Cancer Prevention and Research Institute of Texas, Sante Ventures and Lumira Ventures.

Funding History

GrantNov 2025
$7.1M

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Series B through Grant — per-round amounts, valuations, and who invested in each round.

Investors

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