GORYO Chemical

Goryo Chemical, Inc. is the only manufacturer in Japan specialized in fluorescent dyes. Based in Sapporo, Hokkaido, the company develops and produces highly sensitive and unique fluorescent probes for cellular analysis, assay, and bioimaging applications. Its research reagent portfolio includes products such as AcidiFluor ORANGE, FerroOrange, and FeRhoNox-1, which are used for detecting specific ions and biological markers in live cells. Beyond research reagents, Goryo Chemical has pioneered the concept of 'Navigation Drugs' — activatable fluorescent probes designed to enhance precision in cancer surgery, with programs targeting breast cancer, esophageal cancer, and pancreatic leak detection. The company received an FDA opinion on its navigation drug program and is positioned at the intersection of specialty chemistry, diagnostics, and surgical oncology.